How to Play Guess Who (Board Game). Kids need games! This game is fairly popular. If it looks confusing, you need a guide. This article can guide you into. Guess Who? is a simple two- player game that promotes logical thinking and improves deduction skills in a fun and inventive way. Players sit opposite each other. In Guess Who two teams compete against each other, one trying to hide be able to spot all the differences between a NPC and a Player.